Oberärzte

Prof. Dr. med. habil. Marek Lommatzsch

Leitender Oberarzt der Abteilung Pneumologie

Facharzt für Innere Medizin
Pneumologie
Allergologie

0381 494 7472
0381 494 7393

marek.lommatzsch{bei}med.uni-rostock.de

Curriculum vitae

1994 - 2001Studium Humanmedzin an der Freien Universität Berlin und der Universität Freiburg
2000Promotion "Zur Bedeutung des Brain-derived neurotrophic factor (BDNF) in den inneren Organen unter besonderen Berücksichtigung des allergischen Entzündungsprozesses der Lunge."
2001 - 2003Arzt im Praktikum an der Universität Freiburg und Universität Rostock
seit 2003Arzt in der Abteilung Pneumologie der Universitätsmedizin Rostock
2007Facharzt für Innere Medizin
2008Habilitation "Zur Bedeutung von Neurotrophinen bei respiratorischen Erkrankungen des Menschen".
2009Subspezialist für Innere Medizin / Pneumologie; Funktionsoberarzt der Abteilung Pneumologie
2012Zusatzbezeichnung "Allergologie"; Oberarzt der Abteilung Pneumologie
2013Ernennung zum außerplanmäßigen Professor der Universitätsmedizin Rostock
2021Leitender Oberarzt der Abteilung Pneumologie

            

Mitgliedschaften

  • Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin (DGP)
    • Mitglied der Programmkommission der DGP
  • Deutsche Gesellschaft für Allergologie und Klinische Immunologie (DGAKI)
    • Sprecher der Sektion Pneumologie der DGAKI
  • European Respiratory Society (ERS)
    • Mitglied im Long Range Planning Committee der Sektion "Airway Disease"
  • American Thoracic Society (ATS)
  • American College of Chest Physicians (ACCP)

Publikationen

Overweight is a predictor of long-term survival in hospitalised patients with exacerbations of COPD.
Stoll P, Foerster S, Virchow JC, Lommatzsch M.
Respir Med. 2016 Jul;116:59-62.

Novel strategies for the treatment of asthma.
Lommatzsch M, Stoll P
Allergo J Int 2016;25:11-17

The dendritic cell high-affinity IgE receptor is overexpressed both in asthma and severe COPD.
Stoll P, Bähker A, Ulrich M, Bratke K, Garbe K, Virchow JC and Lommatzsch M
Clin Exp Allergy 2015 (Epub ahead of print), doi:10.1111/cea.12664.

Imbalance of dendritic cell co-stimulation in COPD.
Stoll P, Ulrich M, Bratke K, Garbe K, Virchow JC and Lommatzsch M
Respir Res 2015, 16:19, doi:10.1186/s12931-015-0174-x

Severe asthma: definition, diagnosis and treatment
Lommatzsch M, Virchow JC.
Dtsch Arztebl Int 2014; 111(50): 847-55.

Platelets in asthma: does size matter?
Stoll P, Lommatzsch M.
Respiration. 2014;88(1):22-3.

Vitamin D binding protein and vitamin D in human allergen-induced endobronchial inflammation.
Bratke K, Wendt A, Garbe K, Kuepper M, Julius P, Lommatzsch M, Virchow JC.
Clin Exp Immunol. 2014 Jul;177(1):366-72. 

Impact of smoking on dendritic cell phenotypes in the airway lumen of patients with COPD.
Stoll P, Heinz AS, Bratke K, Bier A, Garbe K, Kuepper M, Virchow JC, Lommatzsch M.
Respir Res. 2014 Apr 18;15:48.

Against all odds: anti-IgE for intrinsic asthma?
Lommatzsch M, Korn S, Buhl R, Virchow JC.
Thorax. 2014. 69(1):94-6.

Medical care for allergic disorders in Germany: a paradox.
Lommatzsch M, Koschel D, Welte T.
Pneumologie. 2013 Dec;67(12):659-61.

Allergic diseases: what is new?
Lommatzsch M.
Dtsch Med Wochenschr. 2013 Dec;138(49):2533-5. 

Fluticasone impact on airway dendritic cells in smokers: a randomized controlled trial
Lommatzsch M, Kraeft U, Troebs L, Garbe K, Bier A, Stoll P, Klammt S, Kuepper M, Bratke K, Virchow JC.
Respir Res. 2013 Oct 29; 14(1):114.

Plasmacytoid dendritic cells in allergic asthma and the role of inhaled corticosteroid treatment.
Bratke K, Prieschenk C, Garbe K, Kuepper M, Lommatzsch M, Virchow JC.
Clin Exp Allergy. 2013 Mar;43(3):312-21.

Stage-dependent association of BDNF and TGF-β1 with lung function in stable COPD.
Stoll P, Wuertemberger U, Bratke K, Zingler C, Virchow JC, Lommatzsch M.
Respir Res. 2012 Dec 17;13:116.

Airway hyperresponsiveness: new insights into the pathogenesis.
Lommatzsch M.
Semin Respir Crit Care Med. 2012 Dec;33(6):579-87.

Plasmacytoid dendritic cells and their Toll-like receptor 9 expression selectively decrease with age.
Garbe K, Bratke K, Wagner S, Virchow JC, Lommatzsch M.
Hum Immunol. 2012 May;73(5):493-7. 

Hypertrophic pulmonary osteoarthropathy as a cue for NSCLC: four cases in the light of the current literature.
Lommatzsch M, Julius P, Lück W, Bier A, Virchow JC.
Pneumologie. 2012 Feb;66(2):67-73.

Bronchoconstriction and airway remodeling.
Lommatzsch M, Kummer W, Virchow JC.
N Engl J Med. 2011 Sep 22;365(12):1156.

Differential effect of clopidogrel and aspirin on the release of BDNF from platelets.
Stoll P, Plessow A, Bratke K, Virchow JC, Lommatzsch M.
J Neuroimmunol. 2011 Sep 15;238(1-2):104-6.

Altered phenotype of blood dendritic cells in patients with acute pneumonia.
Dreschler K, Bratke K, Petermann S, Thamm P, Kuepper M, Virchow JC, Lommatzsch M.
Respiration. 2012;83(3):209-17.

Tiotropium step-up therapy in asthma.
Lommatzsch M, Julius P, Virchow JC.
N Engl J Med. 2011 Feb 10;364(6):578.

Impact of immunotherapy on blood dendritic cells in patients with Hymenoptera venom allergy.
Dreschler K, Bratke K, Petermann S, Bier A, Thamm P, Kuepper M, Virchow JC, Lommatzsch M.
J Allergy Clin Immunol. 2011 Feb;127(2):487-494. 

Differential development of plasmacytoid dendritic cells in Th1- and Th2-like cytokine milieus.
Bratke K, Klein C, Kuepper M, Lommatzsch M, Virchow JC.
Allergy. 2011 Mar;66(3):386-95. 

Purinergic receptor inhibition prevents the development of smoke-induced lung injury and emphysema.
Cicko S, Lucattelli M, Müller T, Lommatzsch M, De Cunto G, Cardini S, Sundas W, Grimm M, Zeiser R, Dürk T, Zissel G, Boeynaems JM, Sorichter S, Ferrari D, Di Virgilio F, Virchow JC, Lungarella G, Idzko M.
J Immunol. 2010 Jul 1;185(1):688-97.

P2X7 receptor signaling in the pathogenesis of smoke-induced lung inflammation and emphysema.
Lucattelli M, Cicko S, Müller T, Lommatzsch M, De Cunto G, Cardini S, Sundas W, Grimm M, Zeiser R, Dürk T, Zissel G, Sorichter S, Ferrari D, Di Virgilio F, Virchow JC, Lungarella G, Idzko M.
Am J Respir Cell Mol Biol. 2011 Mar;44(3):423-9. 

Functional expression of granzyme B in human plasmacytoid dendritic cells: a role in allergic inflammation.
Bratke K, Nielsen J, Manig F, Klein C, Kuepper M, Geyer S, Julius P, Lommatzsch M, Virchow JC.
Clin Exp Allergy. 2010 Jul;40(7):1015-24.

Extracellular adenosine triphosphate and chronic obstructive pulmonary disease.
Lommatzsch M, Cicko S, Müller T, Lucattelli M, Bratke K, Stoll P, Grimm M, Dürk T, Zissel G, Ferrari D, Di Virgilio F, Sorichter S, Lungarella G, Virchow JC, Idzko M.
Am J Respir Crit Care Med. 2010 May 1;181(9):928-34.

Acute effects of tobacco smoke on human airway dendritic cells in vivo.
Lommatzsch M, Bratke K, Knappe T, Bier A, Dreschler K, Kuepper M, Stoll P, Julius P, Virchow JC.
Eur Respir J. 2010 May;35(5):1130-6.

Postpartum venous thromboembolism.
Stoll P, Virchow JC, Lommatzsch M.
N Engl J Med. 2009 Apr 9;360(15):1574.

Thrombomodulin: a novel player in allergic asthma.
Bratke K, Kuepper M, Julius P, Lommatzsch M, Virchow JC.
J Allergy Clin Immunol. 2009 May;123(5):1192.

Adverse effects of salmeterol in asthma: a neuronal perspective.
Lommatzsch M, Lindner Y, Edner A, Bratke K, Kuepper M, Virchow JC.
Thorax. 2009 Sep;64(9):763-9.

Granzyme K: a novel mediator in acute airway inflammation.
Bratke K, Klug A, Julius P, Kuepper M, Lommatzsch M, Sparmann G, Luttmann W, Virchow JC.
Thorax. 2008 Nov;63(11):1006-11.

Function-associated surface molecules on airway dendritic cells in cigarette smokers.
Bratke K, Klug M, Bier A, Julius P, Kuepper M, Virchow JC, Lommatzsch M.
Am J Respir Cell Mol Biol. 2008 Jun;38(6):655-60.

Safety of segmental allergen challenge in human allergic asthma.
Julius P, Lommatzsch M, Kuepper M, Bratke K, Faehndrich S, Luttmann W, Virchow JC.
J Allergy Clin Immunol. 2008 Mar;121(3):712-7.

A role for the neurotrophin receptor TrkB on maturing dendritic cells.
Bratke K, Maruschke L, Darowski M, Kuepper M, Braun A, Virchow JC, Lommatzsch M.
J Neuroimmunol. 2007 Sep;189(1-2):88-94. 

Airway dendritic cell phenotypes in inflammatory diseases of the human lung.
Lommatzsch M, Bratke K, Bier A, Julius P, Kuepper M, Luttmann W, Virchow JC.
Eur Respir J. 2007 Nov;30(5):878-86.

Platelet and plasma BDNF in lower respiratory tract infections of the adult.
Lommatzsch M, Niewerth A, Klotz J, Schulte-Herbrüggen O, Zingler C, Schuff-Werner P, Virchow JC.
Respir Med. 2007 Jul;101(7):1493-9.

Mice running late: T-cell kinetics in models of asthma.
Lommatzsch M, Julius P, Virchow JC.
Am J Respir Crit Care Med. 2007 Mar 1;175(5):522b-523.

Maternal nerve growth factor serum levels in the perinatal period.
Schulte-Herbrüggen O, Litzke J, Hornych K, Zingler C, Höppner J, Virchow JC, Hellweg R, Lommatzsch M.
J Reprod Immunol. 2007 Jun;74(1-2):170-3.

The neural underpinnings of asthma.
Lommatzsch M, Virchow JC.
J Allergy Clin Immunol. 2007 Jan;119(1):254-5.

Dendritic cell subsets in human bronchoalveolar lavage fluid after segmental allergen challenge.
Bratke K, Lommatzsch M, Julius P, Kuepper M, Kleine HD, Luttmann W, Virchow JC.
Thorax. 2007 Feb;62(2):168-75.

The course of allergen-induced leukocyte infiltration in human and experimental asthma.
Lommatzsch M, Julius P, Kuepper M, Garn H, Bratke K, Irmscher S, Luttmann W, Renz H, Braun A, Virchow JC.
J Allergy Clin Immunol. 2006 Jul;118(1):91-7.

Letter regarding article by Ejiri et al, "possible role of brain-derived neurotrophic factor in the pathogenesis of coronary artery disease".
Lommatzsch M, Virchow JC.
Circulation. 2006 Apr 25;113(16):e724.

Maternal serum concentrations of BDNF and depression in the perinatal period.
Lommatzsch M, Hornych K, Zingler C, Schuff-Werner P, Höppner J, Virchow JC.
Psychoneuroendocrinology. 2006 Apr;31(3):388-94.

Regulation of brain-derived neurotrophic factor (BDNF) during sleep apnoea treatment.
Staats R, Stoll P, Zingler D, Virchow JC, Lommatzsch M.
Thorax. 2005 Aug;60(8):688-92.

Neurotrophins in murine viscera: a dynamic pattern from birth to adulthood.
Lommatzsch M, Quarcoo D, Schulte-Herbrüggen O, Weber H, Virchow JC, Renz H, Braun A.
Int J Dev Neurosci. 2005 Oct;23(6):495-500.

A role for brain-derived neurotrophic factor in B cell development.
Schuhmann B, Dietrich A, Sel S, Hahn C, Klingenspor M, Lommatzsch M, Gudermann T, Braun A, Renz H, Nockher WA.
J Neuroimmunol. 2005 Jun;163(1-2):15-23. Epub 2005 Apr 9.

Tumor necrosis factor-alpha and interleukin-6 regulate secretion of brain-derived neurotrophic factor in human monocytes.
Schulte-Herbrüggen O, Nassenstein C, Lommatzsch M, Quarcoo D, Renz H, Braun A.
J Neuroimmunol. 2005 Mar;160(1-2):204-9.

The impact of age, weight and gender on BDNF levels in human platelets and plasma.
Lommatzsch M, Zingler D, Schuhbaeck K, Schloetcke K, Zingler C, Schuff-Werner P, Virchow JC.
Neurobiol Aging. 2005 Jan;26(1):115-23.

Brain-derived neurotrophic factor in platelets and airflow limitation in asthma.
Lommatzsch M, Schloetcke K, Klotz J, Schuhbaeck K, Zingler D, Zingler C, Schulte-Herbrüggen O, Gill H, Schuff-Werner P, Virchow JC.
Am J Respir Crit Care Med. 2005 Jan 15;171(2):115-20.

Nerve growth factor induces increased airway inflammation via a neuropeptide-dependent mechanism in a transgenic animal model of allergic airway inflammation.
Quarcoo D, Schulte-Herbrüggen O, Lommatzsch M, Schierhorn K, Hoyle GW, Renz H, Braun A.
Clin Exp Allergy. 2004 Jul;34(7):1146-51.

Postnatal dexamethasone for lung disease of prematurity.
Lommatzsch M, Klotz J, Virchow JC Jr.
N Engl J Med. 2004 Jun 24;350(26):2715-8.

Brain-derived neurotrophic factor (BDNF) contributes to neuronal dysfunction in a model of allergic airway inflammation.
Braun A, Lommatzsch M, Neuhaus-Steinmetz U, Quarcoo D, Glaab T, McGregor GP, Fischer A, Renz H.
Br J Pharmacol. 2004 Feb;141(3):431-40.

The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in patients with allergic bronchial asthma.
Nassenstein C, Braun A, Erpenbeck VJ, Lommatzsch M, Schmidt S, Krug N, Luttmann W, Renz H, Virchow JC Jr.
J Exp Med. 2003 Aug 4;198(3):455-67.

Neurotrophins in allergic airway dysfunction: what the mouse model is teaching us.
Lommatzsch M, Braun A, Renz H.
Ann N Y Acad Sci. 2003 May;992:241-9.

Nerve growth factor induces airway hyperresponsiveness in mice.
Braun A, Quarcoo D, Schulte-Herbrüggen O, Lommatzsch M, Hoyle G, Renz H.
Int Arch Allergy Immunol. 2001 Jan-Mar;124(1-3):205-7.

Sequential development of airway hyperresponsiveness and acute airway obstruction in a mouse model of allergic inflammation.
Neuhaus-Steinmetz U, Glaab T, Daser A, Braun A, Lommatzsch M, Herz U, Kips J, Alarie Y, Renz H.
Int Arch Allergy Immunol. 2000 Jan;121(1):57-67.

The role of neurotrophins in allergic bronchial asthma.
Braun A, Lommatzsch M, Renz H.
Clin Exp Allergy. 2000 Feb;30(2):178-86.

Abundant production of brain-derived neurotrophic factor by adult visceral epithelia. Implications for paracrine and target-derived Neurotrophic functions.
Lommatzsch M, Braun A, Mannsfeldt A, Botchkarev VA, Botchkareva NV, Paus R, Fischer A, Lewin GR, Renz H.
Am J Pathol. 1999 Oct;155(4):1183-93.

Cellular sources of enhanced brain-derived neurotrophic factor production in a mouse model of allergic inflammation.
Braun A, Lommatzsch M, Mannsfeldt A, Neuhaus-Steinmetz U, Fischer A, Schnoy N, Lewin GR, Renz H.
Am J Respir Cell Mol Biol. 1999 Oct;21(4):537-46.

Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 act as "epitheliotrophins" in murine skin.
Botchkarev VA, Metz M, Botchkareva NV, Welker P, Lommatzsch M, Renz H, Paus R.
Lab Invest. 1999 May;79(5):557-72.

Neurotrophins: a link between airway inflammation and airway smooth muscle contractility in asthma?
Braun A, Lommatzsch M, Lewin GR, Virchow JC, Renz H.
Int Arch Allergy Immunol. 1999 Feb-Apr;118(2-4):163-5.

A new role for neurotrophins: involvement of brain-derived neurotrophic factor and neurotrophin-4 in hair cycle control.
Botchkarev VA, Botchkareva NV, Welker P, Metz M, Lewin GR, Subramaniam A, Bulfone-Paus S, Hagen E, Braun A, Lommatzsch M, Renz H, Paus AR.
FASEB J. 1999 Feb;13(2):395-410.

Neurotrophins are increased in bronchoalveolar lavage fluid after segmental allergen provocation.
Virchow JC, Julius P, Lommatzsch M, Luttmann W, Renz H, Braun A.
Am J Respir Crit Care Med. 1998 Dec;158(6):2002-5.

BDNF overexpression induces differential increases among subsets of sympathetic innervation in murine back skin.
Botchkarev VA, Botchkareva NV, Lommatzsch M, Peters EM, Lewin GR, Subramaniam A, Braun A, Renz H, Paus R.
Eur J Neurosci. 1998 Oct;10(10):3276-83.